A network-based approach to integrate nutrient microenvironment in the prediction of synthetic lethality in cancer metabolism.

Synthetic Lethality (SL) is currently defined as a type of genetic interaction in Methylcobalamin which the loss of function of either of two genes individually has limited effect in cell viability but inactivation of both genes simultaneously leads to cell death.Given the profound genomic aberrations acquired by tumor cells, which can be systemati

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Colliding wall-jets on a cylindrical surface

Paper discusses aerodynamics and potential engineering applications of an unusual and in literature practically unknown fluid flow configuration, with two wall-jets attached Supplement to a cylindrical surface so that they collide head-on and by mutual conjunction generate a single jet directed away from the wall.Applications are envisaged in pneum

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